O3 Ozone Therapy in the Treatment of Alzheimers, Dementia and other Degenrative Neurological Disorders
TREATMENT OF SENILE DEMENTIA OF ALZHEIMER TYPE WITH O3 OZONE THERAPY AND ELECTROMAGNETIC FIELD.
The aim of this study was to introduce a new method of treatment by means of the combination of ozone therapy and electromagnetic field in the therapeutic of the Alzheimer disease, in order to improve the quality of life of these patients.
This study was a prospective trial performed in 60 patients with probable Alzheimer's disease according to NINCDS-ADRDA group criteria. The evaluation of patients included clinical history, exploration of mental status according to Folstein's Minimental Test, Hachinski's isquemic score, the global deterioration scale and the dementia behavior score. Other studies included electroencephalograph, evocated potential (P300) and CT scan of the brain.
The patients were randomly assigned in two treatment groups: Group I: rectal ozone and electromagnetic treatment and Group II: control group. Efficacy assessment was made at 3 months intervals and defined three ranges of responses: improvement, progression and not answer.
Seventy-six percent of the patients who were treated with ozone and electromagnetic field improved after being treated during a month. This response remained in 57,0 % of the patients after six month of treatment. Any improvement was observed in the control group.
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O3 OZONE MEDICAL APPLICATION IN THE TREATMENT OF SENILE DEMENTIA.
In geriatrics, the concept of health is defined in terms of function, the healthy elderly is not that one, who lacks any pathology, but one who has the capacity to autonomy. Dementia is, probably, one of the most fearful diseases for the aging and worse-managed from the clinical point of view, which aggravates still more its prognosis, not only for the patient but also for the society in which he or she lives.
This study is performed by means of the application of daily rectal ozone (20 sessions) to patients suffering from senile dementia (vascular, degenerative or mixed etiology), in doses according to the enzymatic status of each patient.
All elderly persons that assisted to the Geriatric Department in Salvador Allende Hospital, during January/91 to February/95 were evaluated by clinical examination, psychometric tests, Hachinsky Scale, Katz index, Hamilton test (for depressive symptoms) and the Minimental Test (MMT) at the beginning and at the end of the treatment.
An important improvement was attained in the accomplishing of daily life activities, for all kind of dementia, with an enhancement in the quality of life. Any side effect was observed. This therapy is recommended in the treatment of senile dementia.
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O3 OZONE THERAPY IN DEMENTIAL SYNDROME IN THE ELDERLY.
The aim of this paper is to evaluate the effectiveness of ozone therapy in demential syndrome, in the elderly, during two years.
Clinical, neurophysiological and psicological evaluations, before and after ozone therapy, were performed and an evaluation criterion was defined. 30 patients were studied, 60 % represented the male sex and 40 % the female sex (70 % between 60 and 79 years old). According to the ethiology, Alzheimer dementia, multi-infarction dementia and vascular epilepsy were present.
Improvement in 21 patients (70 %) was achieved, 7 patients (23 %) remained the same and 2 patients (7 %) got worse. It is recommended the generalization of this therapeutic protocol.
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O3 OZONE THERAPY IN THE TREATMENT OF ELDERLY PATIENTS SUFFERING FROM PARKINSON'S SYNDROMES.
Parkinson's syndromes are present frequently in the third age, with a high tendency to produce disability. The aim of this paper is to study the effectiveness of ozone therapy in the improvement of the elderly autonomy, as well as the quality of life of patients suffering of Parkinson's disease, taking into account some therapeutical properties of ozone (increase of the antioxidant defense system, enhancement in the tissue oxygenation, metabolic modulation, improvement of the neuroplasticity phenomenom, etc.).
A sample of 80 patients with Parkinson's syndromes of different nature were treated with rectal ozone (during 15 sessions) and physiotherapy. A complete neurologic and psychometric examination (Minimental test, Katz index, multidimensional evaluation, etc.) was performed in each patient, at the beginning and at the end of the treatment.
The results demonstrated that all symptoms and signs studied improved after the treatment, fundamentally the rigidity (95.7 %), the gait (95.3 %) and the bradiphrasia (88.8 %).
The Daily Life Activities improved in 95 % of the treated patients. Any side-effect or intolerance were observed during the treatment. In general, an improvement in the quality of life of these patients, increasing their autonomy for a much longer period was achieved.
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OZ-PO-052: O3 OZONE AND ELECTROMAGNETIC FIELD IN THE TREATMENT OF ALZHEIMER'S DISEASE.
Alzheimer's disease (AD) is a growing problem worldwide in the medical, psychiatric, neurological, epidemiological, economic and fundamentally human. Free radicals that cause membrane lipid peroxidation, disruption of nucleic acids, protein oxidation, is one of the etiopathogenic factors in AD.
Given that ozone is able to activate antioxidant defense systems, and improve tissue oxygenation study was conducted in 45 patients with senile dementia of Alzheimer type likely.
Patients were divided randomly into three groups: ozone (rectally), magnetic and combined treatment. We defined three types of response: regression or improvement, progression, and no answer, according to the scale of global impairment and age-dependent Alzheimer's disease (GDS) and the mini-mental state examination and the relative standard and the medical team as to improvement in psychiatric and behavioral manifestations and other parameters that measure quality of life.
Response was obtained regression or improvement in 60% of cases with combined magnetic and ozone therapy, a month of treatment, which was maintained in 46.6% of patients still at six months of treatment, no response was obtained with the use of magnetic field or ozone as isolated methods.
There were no subsequent manifestations of toxicity that forced the suspension of treatment.
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